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Astotherm Plus, Astotubes, Astoline

FDA 510(k)FDA UDIEUDAMED

Class II (US FDA 510(k))

510(k) K991160Ref AP220SEURef AP220SUKRef AP220CNRef AP220CHRef AP220SDKRef AP220SCN

by Stihler Electronic Gmbh

Identity

Trade Name
ASTOTHERM PLUS EUDAMED
ASTOTHERM® PLUS FDA UDI
Generic Name
Conduction blood/fluid warmer FDA UDI
Device Name
ASTOTHERM PLUS control unit EUDAMED
ASTOTHERM PLUS EUDAMED
Blood and infusion warmer FDA UDI
Model / Reference
AP220SEU EUDAMEDFDA UDI
AP220SUK EUDAMEDFDA UDI
AP220CN EUDAMED
AP220CH EUDAMED
AP220SDK EUDAMED
AP220SCN EUDAMED
Description
Blood and infusion warmer FDA UDI

Identifiers

Catalog Number
AP220SEU FDA UDI
AP220SUK FDA UDI
Primary DI / UDI-DI
04260114140382 EUDAMEDFDA UDI
04260114140474 EUDAMEDFDA UDI
04260114140979 EUDAMED
04260114140962 EUDAMED
04260114141020 EUDAMED
04260114141013 EUDAMED
Basic UDI-DI
B-04260114140382 EUDAMED
B-04260114140474 EUDAMED
B-04260114140979 EUDAMED
B-04260114140962 EUDAMED
B-04260114141020 EUDAMED
B-04260114141013 EUDAMED
510(k) Number
K991160 FDA 510(k)FDA UDI
FDA Product Code
BSB FDA 510(k)FDA UDI
EMDN Code
A030105 FLUIDS HEATING SYSTEMS EUDAMED
GMDN Term
Conduction blood/fluid warmer FDA UDI

Classification

Device Class
Class IIb EUDAMED
Class II FDA 510(k)FDA UDI
Legislation / Framework
21 CFR Part 864.9205 FDA 510(k)
Regulation Number
864.9205 FDA 510(k)FDA UDI
Market of Registration
Germany EUDAMED
Northern Ireland EUDAMED
Denmark EUDAMED
Advisory Committee
Hematology FDA 510(k)
FDA Decision
SESE Substantially Equivalent FDA 510(k)
Commercial Distribution
In Commercial Distribution FDA UDI

Clinical & Handling

Sterile

No

EUDAMEDFDA UDI

Single Use

No

FDA UDI

Implantable

No

EUDAMEDFDA UDI

Reusable

No

EUDAMED

Contains Latex

No

EUDAMEDFDA UDI

Reprocessed

No

EUDAMED

Human-derived

No

EUDAMED

Human Tissues

No

EUDAMED

Animal Tissues

No

EUDAMED

Administering Medicine

No

EUDAMED

Measuring Function

No

EUDAMED

Incorporates Medicinal Product

No

EUDAMED

Prescription Use

Yes

FDA UDI

Over-the-Counter

No

FDA UDI

Convenience Kit

No

FDA UDI

Combination Product

No

FDA UDI

HCT/P

No

FDA UDI

Premarket Exempt

No

FDA UDI

Lot / Batch Number

No

FDA UDI

Serial Number

Yes

FDA UDI

Expiration Date

No

FDA UDI

Manufacturing Date

Yes

FDA UDI

The Astotherm Plus, Astotubes, and Astoline are Blood Warmers, Non-Electromagnetic Radiation designed to maintain and elevate the temperature of blood and intravenous infusions during clinical procedures. These devices ensure thermal regulation to mitigate perioperative hypothermia by warming fluids to safe, physiologically compatible levels prior to administration.

Supplied as a modular system, the Astotherm Plus includes reusable warming units (Astoline) and single-use warming tubes (Astotubes) for compatibility with standard transfusion and infusion lines. The system operates in operating rooms (OR) and intensive care units (ICU), with models like the AP220 achieving operational readiness in under 60 seconds. Authorized under FDA 510(k), MDD, and MDR, these devices adhere to Class II regulatory standards (864.9205) and are intended for single-use components (Astotubes) while the Astoline warming unit is reusable. Storage and handling follow sterile protocols for single-use components, with no MRI safety restrictions.

Frequently asked questions

What clinical settings are the Astotherm Plus system and its components designed to operate in?

The Astotherm Plus system, including the Astoline warming unit and Astotubes, is specifically designed for use in operating rooms (OR) and intensive care units (ICU). These environments require precise temperature control for blood and intravenous infusions to prevent perioperative hypothermia, ensuring fluids are warmed to safe, physiologically compatible levels before administration.

Are the Astotubes single-use or reusable, and how does this affect their handling and storage?

The Astotubes are intended for single-use only, meaning each tube is designed to be discarded after one use. This requires adherence to sterile protocols during storage and handling to maintain safety and efficacy. The reusable component of the system, the Astoline warming unit, can be used repeatedly, but the single-use tubes must be replaced after each procedure.

How quickly can the Astotherm Plus system be prepared for use, and what does this mean for clinical workflow?

The Astotherm Plus system, specifically the AP220 model, is noted for achieving operational readiness in under 60 seconds. This rapid setup time helps streamline clinical workflows in time-sensitive environments like operating rooms or intensive care units, reducing delays in warming blood or intravenous infusions before administration.

What regulatory standards does the Astotherm Plus system comply with, and what does this imply about its safety and approval process?

The Astotherm Plus system, including the Astoline and Astotubes, is authorized under FDA 510(k), MDD, and MDR regulations, adhering to Class II standards (864.9205). This classification implies that the device has undergone rigorous review by regulatory bodies to ensure its safety and effectiveness for maintaining and elevating the temperature of blood and infusions, while also meeting specific performance and manufacturing requirements.

Can the Astotherm Plus system be used with standard transfusion and infusion lines, and how does the modular design support compatibility?

Yes, the Astotherm Plus system is designed to be compatible with standard transfusion and infusion lines. The modular system includes reusable warming units (Astoline) and single-use warming tubes (Astotubes), allowing for easy integration with existing clinical setups. This flexibility ensures seamless use in various medical procedures where precise temperature control of fluids is required.

This description and any FAQs above were generated automatically from registry data and have not been verified by the manufacturer or by deviCERTS. Always check the official registry entry and the manufacturer's instructions for use before relying on them. Sources consulted: Astotherm® Plus - Gentherm Medical, PDF ASTOTHERM® plus Rapid, safe and highly efficient warming of blood and ..., ASTOTHERM PLUS, ASTOTUBES, ASTOLINE (K991160) — FDA 510 (k) | Innolitics

Authorization Coverage (2 countries)

Regulatory Authorizations

European Union Active

MDD

European Union Active

MDR

United States Active

FDA_510K

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Manufacturer

Sources (9)

  • FDA 510(k) K991160 24 fields · synced Sep 18, 2026
  • FDA UDI e75e056a-f258-458e-9055-3d56918fdde1 35 fields · synced May 30, 2026
  • FDA UDI 0482c04b-c4d4-4f08-9316-984fd0f1148f 35 fields · synced May 30, 2026
  • EUDAMED 139b807f-556f-47c9-bb73-21b144fe8432 61 fields · synced Jul 9, 2026
  • EUDAMED f97120d7-9305-485e-a13f-1cd0b5c0a8c8 61 fields · synced Jul 11, 2026
  • EUDAMED 1441f391-890e-4e6c-8e09-e10198295131 61 fields · synced Jul 15, 2026
  • EUDAMED 2d3d54f4-736d-4ee1-afcd-4776cc66a872 61 fields · synced Jul 24, 2026
  • EUDAMED 572ef211-055b-4e32-9bda-469adce8a2ca 61 fields · synced Aug 2, 2026
  • EUDAMED eddc0bf4-2916-4f65-88a6-c721d8c6f288 61 fields · synced Aug 4, 2026